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5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."

J Child Adolesc Psychopharmacol

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(1992) Effects of vitamin B12 on plasma melatonin rhythm in humans: increased light sensitivity phase-advances the circadian clock